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CRISPR Gene Editing

Concept

About

CRISPR gene editing is a revolutionary biotechnology tool that enables precise modifications to the DNA of living organisms. This technique is based on a bacterial defense system, where CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) arrays are used to remember and combat viral infections. By adapting this system, scientists can use CRISPR-Cas9 to cut DNA at specific locations, allowing for the addition, removal, or alteration of genetic material. This has opened new avenues for treating genetic disorders, such as sickle cell disease, by correcting harmful mutations. CRISPR's precision and efficiency have transformed genetic research and medical treatment. It is used to study diseases, develop new medicines, and engineer crops and livestock. CRISPR can also "knock out" genes or modify their expression, offering potential treatments for complex diseases like cancer and HIV. However, its use raises ethical concerns, particularly regarding germline editing, which could affect future generations. Despite these challenges, CRISPR remains a powerful tool for advancing biotechnology and medicine.