Best biotechnology companies for healthcare in Spain

With over 30 years of experience, Eurofins Ingenasa develops and manufactures diagnostic kits. Its commitment to research allows it to offer fundamental assays for the detection of pathologies.

This center is a benchmark in fundamental and applied research, driving biotechnological solutions in health. Its commitment to training and knowledge transfer positions it as a key driver in the sector.

Helix BioS specializes in the manufacturing of biological and diagnostic products, including antibodies and proteins. Its expertise is crucial for research and diagnosis, positioning it among the best in Madrid.

Macrogen is a reliable partner in genetic science, collaborating with the academic and pharmaceutical sectors. Its constant innovation and attention to quality make it one of the best biotechnology companies in Madrid.

Lyposmol Biotech focuses on R&D&i of new technologies for regenerative and genetic medicine. Its projects improve the efficacy and safety of therapies, providing innovative solutions to the global market.

Leader in immunological medicine with its VIVA-ELISA® technology, it has been recognized among the TOP 100 startups by APTE. Its contribution to the science and innovation ecosystem is remarkable.

This spin-off from the University of Lleida focuses on solutions for metastatic melanoma. It combines scientific research with real-world application in oncology, with enormous clinical potential.

Horus ML applies machine learning to clinical processes to improve decision-making in healthcare. Its value lies in the integration of artificial intelligence to optimize healthcare.

Better Care is a platform that connects medical devices and centralizes data to monitor patients in real time. Its ability to work with real-time data improves hospital efficiency.

D-Sight develops neuroprotective ocular therapies for vision diseases. It is a biotechnology company applied to a very specific problem, with great potential if clinical validation progresses.

SleepOne works on technological solutions for the diagnosis and treatment of sleep disorders. It addresses a growing and often inefficiently treated health problem, with ample room for robust solutions.

Oncoviva is a startup focused on oncology solutions, with a focus on improving diagnosis and treatment. Oncology is a field of high need and impact where a large part of biotechnological innovation is concentrated.

Minoryx is a relevant player in the Spanish biotech ecosystem, focused on drugs for rare diseases. It participates in key discussions on accelerating biomedical innovations.

53Biologics specializes in the development and manufacturing of biological drugs (GMP biomanufacturing). Its recent investment and expansion position it as a key player in biopharmaceutical production.

Arthex Biotech is dedicated to the development of a new drug for muscular dystrophy type 1 (DM1). Its focus on a rare disease with high unmet medical need gives it great potential for impact.

Biofabri is a success story in the Spanish biotechnology sector, developing and manufacturing state-of-the-art biotechnological products. Its solid business model is based on innovation.

Gazella Biotech investigates new therapies for metabolic pathologies such as resistant obesity. Its precise targeting approach to metabolic regulatory centers positions it in a massive market.

Biorce applies artificial intelligence and real-world data to transform clinical trials. Its data-driven approach accelerates the transition from lab to patient, optimizing design and recruitment.

ReProteinAll develops 'soft nanopore' technology for protein purification and refolding. Its system improves yields in protein production, a critical aspect in biopharmaceutical manufacturing.

UCB Biopharmaceuticals has been recognized as one of the best places to work in Spain in 2026. This indicates a strong organizational culture and its attractiveness for talent in the biotechnology sector.