Essential weapons for end-game content in Destiny 2

Apex Predator is a top-tier rocket launcher, especially relevant in the current PvE DPS meta where rocket launchers dominate. Its ability to roll with Reconstruction and Bait and Switch makes it highly effective for sustained boss damage.

The Navigator is an excellent exotic trace rifle for end-game content, particularly for Strand builds. It provides the strong Woven Mail buff, offering significant protection and survivability, which is crucial in challenging activities.

The M17 Fast Talker is literally the best kinetic SMG for boss DPS and orb generation in the game. Its unique heat bonus frame and powerful perk rolls make it an S-tier primary for challenging end-game content.

Indebted Kindness is an incredibly strong rocket-assisted sidearm, especially for double special builds. It excels in add clear, offers great ammo efficiency, and provides versatility for engaging enemies at various ranges, making it a top choice for challenging content.

Rufus's Fury is widely regarded as the best legendary auto rifle for PvE content. Its craftable nature and powerful perk combinations like Reconstruction and Target Lock make it a reliable workhorse weapon for consistent damage and efficient add clearing.

Ulterior Observation is a new Stasis Machine Gun from the Edge of Fate expansion, offering fast, hard-hitting bursts. It's excellent for steady clearing, sustained fire, and freezing synergy, making it a strong choice for activities prioritizing control and uptime.

Witherhoard remains one of the most versatile and reliable special weapons in Destiny 2. Its persistent damage-over-time blight pools are exceptional for both boss DPS support and efficient add clearing, making it a consistent choice for end-game activities.

Divinity is an indispensable exotic trace rifle for end-game PvE content, especially raids and dungeons. Its unique ability to create a critical hit spot on enemies significantly boosts team damage, making it a crucial support weapon for high-DPS strategies.

Cold Comfort is currently considered the best heavy weapon for boss encounters in raids and dungeons. Its powerful perk combination of Envious Assassin and Bait and Switch allows for significant damage without frequent reloads, making it a top-tier choice for DPS.

Forbearance is an Arc Wave Frame Grenade Launcher that is ridiculously effective for clearing enemies in end-game content. Its unique wave-clearing ability makes it unparalleled for add control and quickly dispatching large groups of foes.

Gjallarhorn remains a top-tier heavy weapon, particularly for boosting team rocket launcher damage. Its unique Wolfpack Rounds and ability to grant them to allies make it an essential pick for maximizing burst DPS in many end-game encounters.

The Hothead is a re-issued rocket launcher that consistently ranks among the best for DPS in the current meta. Its ability to roll with powerful damage and reload perks makes it a versatile and high-performing option for boss encounters.

Quicksilver Storm is the best Exotic Auto Rifle for PvE content, offering excellent versatility. It's highly effective for clearing large groups of enemies and quickly eliminating bigger foes, making it a strong primary choice for end-game activities.

The Call is the first kinetic slot rocket sidearm, making it incredibly strong and uniquely useful for end-game content. Rocket sidearms are powerful, and its kinetic slot placement provides unique buildcrafting opportunities with perks like Lead from Gold and Slice.