Innovative companies developing biotechnological products in Spain

Explore pioneering enterprises at the forefront of biotechnology within Spain. This ranking highlights cutting-edge firms focused on research, development, and commercialization of advanced biotechnological solutions. Discover entities driving progress in areas like pharmaceuticals, diagnostics, agricultural biotechnology, and industrial applications, contributing to scientific advancement and economic growth. Ideal for investors, job seekers, and industry professionals interested in the Spanish biotech ecosystem.

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  1. 1

    Vivia Biotech (Madrid, Madrid)

    325 Global Votes
    • Specializes in producing TILs from diverse solid tumor indications

      (+4)

    Vivia Biotech contributes significantly to medical diagnostics, particularly in the critical area of blood cancers. The company develops *ex vivo* assays for hematologic malignancies, aiding in better diagnosis and treatment strategies.

  2. 2

    Biofabri (O Porriño, Pontevedra)

    217 Global Votes
    • Researches and develops new vaccines and immunotherapy products

      (+4)

    Biofabri is at the forefront of global health innovation with its MTBVAC, the only live-attenuated TB vaccine candidate derived from *Mycobacterium tuberculosis* in advanced clinical trials. Its progression into large-scale Phase 3 trials and global manufacturing plans for 2026 underscore its potential to address a critical unmet medical need.

  3. 3

    Arthex Biotech (Valencia, Valencia)

    0 Global Votes
    • Develops targeted RNA medicines

      (+3)

    Arthex Biotech is a leading biotechnology company specializing in RNA-based therapies for rare genetic diseases. Its ATX-01 treatment for Myotonic Dystrophy Type 1 is advancing towards clinical phases, backed by significant funding.

  4. 4

    Biolan Microbiosensores, S.L. (Derio, Vizcaya)

    0 Global Votes
    • Develops, manufactures, and markets analytical and diagnostic methods

      (+4)

    Biolan Microbiosensores is recognized for its ongoing innovation in food technology, actively developing and manufacturing biosensors. These biosensors are crucial for ensuring food safety and quality across various industries.

  5. 5

    OXOlife (Barcelona, Barcelona)

    0 Global Votes
    • Develops oral drug to enhance embryo implantation

      (+4)

    OXOlife is developing a reproductive drug aimed at enhancing female fertility, addressing a significant area in healthcare. Its focus on improving embryo implantation and restoring ovulation positions it as a promising biotech startup for 2026.

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  7. 6

    Cebiotex (Cantabria, Spain)

    0 Global Votes
    • Develops innovative local therapies for oncology

      (+4)

    Cebiotex is innovating in drug delivery through its specialized electrospun nanofiber technology. The company offers both manufacturing technology and contract research, making it a key player in advanced pharmaceutical development.

  8. 7

    3P Biopharmaceuticals (Noáin (Valle de Elorz) – Noain (Elortzibar), Pamplona)

    0 Global Votes
    • End-to-end global CDMO providing integrated solutions

      (+4)

    3P Biopharmaceuticals is a crucial contract development and manufacturing organization (CDMO) supporting the broader biotech industry. It provides essential services for the production of various biopharmaceuticals, including vaccines and recombinant proteins.

  9. 8

    DNActive (Granada, Spain)

    0 Global Votes
    • Unique fermented DNA from salmon milt ingredient

      (+4)

    DNActive is an innovative company in personalized healthcare, offering genetic tests to determine predisposition to major diseases. Its focus on genetic analysis contributes significantly to preventive and personalized medicine.

  10. 9

    SpliceBio (Barcelona, Spain)

    0 Global Votes
    • Harnesses proprietary Protein Splicing platform

      (+4)

    SpliceBio is a promising gene therapy company utilizing proprietary intein platform technology to develop novel treatments. Its focus on incurable genetic diseases positions it at the forefront of advanced biotechnological solutions.

  11. 10

    Biorizon Biotech (Granada, Spain)

    0 Global Votes
    • Develops biotechnological solutions for sustainable agriculture

      (+4)

    Biorizon Biotech provides innovative biotechnology solutions for the agricultural sector, focusing on ecological agriculture and sustainable farming practices. Its biostimulants contribute to environmentally friendly cultivation.

  12. 11

    Corify Care (Valencia, Valencia)

    0 Global Votes
    • Develops non-invasive cardiac mapping medical device

      (+4)

    Corify Care is developing the ACORYS® system, an innovative medical technology for diagnosing and treating cardiac arrhythmias. With recent funding, the company is set to expand its non-invasive heart mapping technology across Europe.

  13. 12

    Evolving Therapeutics (Valencia, Valencia)

    0 Global Votes
    • Develops bacteriophage-based therapies

      (+4)

    Evolving Therapeutics is addressing the critical issue of antibiotic resistance through advanced phage therapy. As a spin-off from the University of Valencia, its research in combating multi-resistant bacteria is highly innovative and timely.

  14. 13

    Quibim (Valencia, Valencia)

    0 Global Votes
    • Pioneering quantitative imaging biomarkers

      (+4)

    Quibim is a leading European reference in advanced medical imaging analysis, developing AI-based biomarkers and human digital twins. Its significant funding and focus on AI are revolutionizing personalized medicine.

  15. 14

    INBRAIN Neuroelectronics (Barcelona, Catalonia)

    0 Global Votes
    • Develops breakthrough neuroelectronic therapies

      (+4)

    INBRAIN Neuroelectronics is highly innovative in neurotechnology, developing graphene-based brain-computer interfaces for therapeutic use. Its intelligent neural platforms aim to treat complex neurological conditions by precisely modulating brain activity.

  16. 15

    Biorce (Spain)

    0 Global Votes
    • Builds AI software for clinical trials

      (+4)

    Biorce is an innovative company applying AI to accelerate clinical drug trials, addressing a major bottleneck in pharmaceutical development. Its platform optimizes research processes, aiming to reduce costs and speed up market launch.

  17. 16

    Natac Biotech (Hervás, Cáceres)

    0 Global Votes
    • Specialized in sustainable plant extracts

      (+4)

    Natac Biotech is a key player in the bioeconomy, specializing in botanical extracts and natural ingredients, and leading the SustaiNext initiative. Its transformation into an extract biorefinery with significant European funding highlights its commitment to sustainable innovation.

  18. 17

    Cellerix (Madrid, Madrid)

    0 Global Votes
    • Develops innovative medicines based on stem cells

      (+4)

    Cellerix is at the forefront of regenerative medicine and cell therapy in Spain, developing medicines based on adult stem cells. Its products, like Cx401 and Cx501, target complex conditions in gastroenterology and dermatology.

  19. 18

    NIMGenetics (Madrid, Madrid)

    0 Global Votes
    • Specialised in clinical genetic diagnosis products and services

      (+1)

    NIMGenetics provides advanced genetic diagnostic solutions crucial for personalized medicine and early detection. Its products, like TRISONIM and ONCONIM, utilize microarray and next-generation sequencing technologies for prenatal, neonatal, and oncology applications.

  20. 19

    BioTech Foods (San Sebastián, Guipúzcoa)

    0 Global Votes
    • Pioneers in cell culture technology

      (+4)

    BioTech Foods is a pioneering company in the cultivated meat sector, utilizing advanced cell culture technology to produce sustainable protein. Its innovative approach addresses the growing demand for safer and more environmentally friendly food sources.

  21. 20

    DeepUll (Barcelona, Catalonia)

    0 Global Votes
    • Develops technology for pathogen identification

      (+4)

    DeepUll is developing a critical new diagnostic system for early-stage sepsis, a life-threatening condition. Its technology aims to quickly identify pathogens and predict sepsis evolution, significantly improving patient outcomes.