Leading companies in longevity and anti-aging

Explore the forefront of the longevity sector, identifying key companies driving innovation in anti-aging research, biotechnology, and health technologies. This ranking highlights businesses developing groundbreaking therapies, products, and services aimed at extending human lifespan and improving healthspan. Discover leaders in pharmaceuticals, nutraceuticals, regenerative medicine, and digital health solutions focused on delaying age-related diseases and enhancing vitality. Uncover the firms making significant advancements in understanding and reversing the aging process, from cellular rejuvenation to personalized wellness programs. This resource is ideal for investors, health enthusiasts, and professionals interested in the future of aging and health.

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  1. 1

    BioAge Labs

    351 Global Votes
    • Develops therapies targeting the biology of human aging

      (+4)

    BioAge Labs uses artificial intelligence and omics data to identify aging biomarkers and develop drugs. Its focus on AI-driven drug discovery for aging pathways makes it a promising company.

  2. 2

    Grupo Neolife (Spain)

    104 Global Votes
    • First longevity clinic in Spain

      (+4)

    Grupo Neolife is a specialist in preventive anti-aging medicine in Spain, offering advanced check-ups and personalized hormone therapy programs. Their focus on preventive medicine and age management positions them as leaders in the field of longevity in Spain.

  3. 3

    Altos Labs (2021)

    0 Global Votes
    • Raised $3 billion in initial funding

      (+4)

    Altos Labs is a pioneering company in cellular rejuvenation therapies, focusing on epigenetic reprogramming to reverse aging at a molecular level. Its unprecedented funding and expected human clinical trials by 2026 position it as a leader.

  4. 4

    Retro Biosciences (2021)

    0 Global Votes
    • Developing therapies for diseases driven by aging

      (+4)

    Retro Biosciences invests heavily in plasma-based therapies and cellular repair technologies, with the goal of extending healthy lifespan by 10 years. In 2026, they are expected to announce clinical trial results that could be revolutionary.

  5. 5

    Life Biosciences (2017)

    0 Global Votes
    • Pioneering cellular rejuvenation therapies

      (+4)

    Co-founded by David Sinclair, this company focuses on cellular rejuvenation therapies through partial epigenetic reprogramming. In January 2026, the FDA authorized human clinical trials for its gene therapy ER-100, a significant milestone.

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  7. 6

    Cambrian Biopharma

    0 Global Votes
    • Develops first-in-class small molecule inhibitors

      (+4)

    Cambrian Biopharma operates as a 'company builder,' funding multiple therapeutic programs simultaneously, from senescent cell clearance to immunological rejuvenation. Its distributed R&D model makes it a central player in longevity biotechnology.

  8. 7

    Gero (2025)

    0 Global Votes
    • Targets the root physics of aging

      (+4)

    Gero is an AI-driven drug discovery company focused on age-related diseases. In July 2025, it announced a research and licensing agreement with Chugai Pharmaceutical, validating its AI platform.

  9. 8

    Turn Biotechnologies (2020)

    0 Global Votes
    • Develops mRNA medicines

      (+2)

    Turn Biotechnologies develops epigenetic reprogramming technologies and mRNA-based therapies for age-related diseases. In March 2025, it acquired technology to enhance the delivery of its therapies, demonstrating continuous progress.

  10. 9

    Rubedo Life Sciences (2025)

    0 Global Votes
    • Premier longevity company

      (+4)

    Rubedo Life Sciences develops therapies that selectively eliminate senescent cells, the 'zombie cells' that contribute to aging. In May 2025, it received FDA authorization for its drug RLS-1496, with a Phase 1b/2a study planned.

  11. 10

    Calico Life Sciences (2013)

    0 Global Votes
    • Focuses on the biology of aging

      (+4)

    Calico Labs, an Alphabet (Google) project, focuses on understanding the molecular mechanisms of aging and developing technologies to extend lifespan. Its partnership with AbbVie for neurodegenerative treatments keeps it relevant in 2026.

  12. 11

    Oisín Biotechnologies (2026)

    0 Global Votes
    • Pioneers genetic medicines for age-related diseases

      (+4)

    Oisín Biotechnologies develops anti-aging treatments that eliminate senescent cells, which contribute to age-related diseases. By 2026, its drug delivery platform has entered Phase 1 trials for cardiovascular aging, highlighting it in the field.

  13. 12

    Unity Biotechnology (2009)

    0 Global Votes
    • Develops therapeutics to slow, halt, or reverse diseases of aging

      (+3)

    Unity Biotechnology specializes in senescence-targeted therapies, developing drugs to eliminate senescent cells that drive aging. It continues to be a key player in the development of senolytics, aiming to delay or reverse aging diseases.

  14. 13

    Insilico Medicine (2026)

    0 Global Votes
    • Unique approach to identifying therapeutic targets for aging

      (+4)

    Insilico Medicine combines artificial intelligence with biology to discover new longevity treatments. In 2026, its first AI-discovered drug is in Phase 2 trials, attracting attention as a promising longevity action.

  15. 14

    Human Longevity Inc. (2026)

    0 Global Votes
    • Leverages precision longevity technologies

      (+4)

    Human Longevity Inc. is a genomics-based health intelligence company that empowers proactive healthcare. It focuses on shifting medicine from reactive to proactive for diseases like cancer and diabetes, making it relevant in today's longevity landscape.

  16. 15

    BioViva USA Inc. (2015)

    0 Global Votes
    • Develops gene therapies targeting cellular aging

      (+4)

    BioViva USA Inc. is a leader in gene therapy innovation, seeking to treat severe genetic disorders and cellular aging. Its focus on gene therapy for cellular aging keeps it at the forefront of longevity solutions in 2026.

  17. 16

    Cenegenics (2026)

    0 Global Votes
    • Focuses on functional longevity and extending healthspan

      (+4)

    Cenegenics is a pioneer in longevity medicine with over 25 years of experience in age management. They offer advanced medical therapies and preventive check-ups based on biomarkers, providing a guided 360° clinical approach to longevity.