
Japanese Encephalitis Vaccine
Medical conceptAbout
The Japanese Encephalitis (JE) vaccine is a crucial preventive measure against Japanese Encephalitis, a serious viral infection transmitted by mosquitoes, primarily in rural Asia. Two main types of vaccines are available: inactivated vaccines like JEspect and live attenuated vaccines like Imojev. JEspect is administered in two doses, 28 days apart, with a booster recommended after 12-24 months if exposure continues. It is effective for individuals aged 2 months and older, though primarily licensed for those over 18. JE vaccines are recommended for travelers to endemic areas, especially those staying for more than a month or engaging in outdoor activities. They are also advised for laboratory workers and individuals living in high-risk zones. While generally safe, live vaccines like Imojev are contraindicated in pregnant or immunocompromised individuals. Preventing mosquito bites remains a key strategy alongside vaccination. The vaccines offer significant protection, with effectiveness rates of 94% to 96% depending on the type and dosing schedule.